Anti-Human Endoglin/CD105 Polyclonal Antibody (HB604014)

Name: Anti-Human Endoglin/CD105 Polyclonal Antibody
Brand: abinScience
SKU: HB604014
Price: 168 USD
Availability: InStock

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Aperçu

Numéro de catalogue

HB604014

Description

Anti-CD105/ENG Polyclonal Antibody (HB604014) is a rabbit polyclonal antibody detecting CD105 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human CD105/ENG (Thr27-Gly581).

Cible

CD105, END, Endoglin, ENG

Purification

Purified by antigen affinity column.

Numéro d'accès

P17813

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.

1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454

2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529

3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484

4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773

5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830

6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366

7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410

Note

For research use only.

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