Anti-Human Endoglin/CD105 Polyclonal Antibody (HB604014)

Name: Anti-Human Endoglin/CD105 Polyclonal Antibody
Brand: abinScience
SKU: HB604014
Price: 168 USD
Availability: InStock

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概要
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参考文献
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概要

カタログ番号

HB604014

説明

Anti-CD105/ENG Polyclonal Antibody (HB604014) is a rabbit polyclonal antibody detecting CD105 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

種反応性

Human

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human CD105/ENG (Thr27-Gly581).

ターゲット

CD105, END, Endoglin, ENG

精製

Purified by antigen affinity column.

アクセッション番号

P17813

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.

1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454

2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529

3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484

4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773

5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830

6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366

7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410

注意事項

For research use only.

イメージ

参考文献

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