Anti-CD94/KLRD1 Polyclonal Antibody (HC299014)

Name: Anti-CD94/KLRD1 Polyclonal Antibody
Brand: abinScience
SKU: HC299014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HC299014

Descripción

Anti-CD94/KLRD1 Polyclonal Antibody (HC299014) is a rabbit polyclonal antibody detecting KLRD1 in ELISA, IHC, WB. Suitable for Human, Macaca mulatta, Pan troglodytes, and Pongo pygmaeus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human CD94/KLRD1 (Lys32-Ile179).

Objetivo

Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, Natural killer cells antigen CD94, CD94, KP43, KLRD1

Purificación

Purified by antigen affinity column.

Número de acceso

Q13241

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Natural killer cells antigen CD94 (KLRD1) is a ~20 kDa protein. Immune receptor involved in self-nonself discrimination. In complex with KLRC1 or KLRC2 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia and non-classical MHC class Ib molecules. Enables cytotoxic cells to monitor the expression of MHC class I molecules in healthy cells and to tolerate self. Primarily functions as a ligand binding subunit as it lacks the capacity to signal.

1. Boyington, JC. et al. (1999) Immunity 10, 75-82. PMID: 10023772

2. Bhagat, G. et al. (2008) The Journal of clinical investigation 118, 281-93. PMID: 18064301

3. Sullivan, LC. et al. (2007) Immunity 27, 900-11. PMID: 18083576

4. Lin, Z. et al. (2023) Nature immunology 24, 1087-1097. PMID: 37264229

5. Braud, VM. et al. (1998) Nature 391, 795-9. PMID: 9486650

6. Llano, M. et al. (1998) European journal of immunology 28, 2854-63. PMID: 9754572

7. Jabri, B. et al. (2002) Immunity 17, 487-99. PMID: 12387742

8. Valiante, NM. et al. (1997) Immunity 7, 739-51. PMID: 9430220

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-CD94/KLRD1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

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