Human CD94/KLRD1 Recombinant Protein (C-Fc) (HC299011)

Name: Human CD94/KLRD1 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HC299011
Price: 298 USD
Availability: InStock

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Overview

Catalog No.	HC299011
Description	Recombinant Human CD94/KLRD1 Protein, C-Fc (HC299011) expressed in Mammalian Cells, spanning Lys32-Ile179. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	Mammalian cells
Accession	Q13241
Protein length	Lys32-Ile179
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	45.50 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	CD94, KLRD1, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, Natural killer cells antigen CD94
Background	Natural killer cells antigen CD94 is a ~20 kDa protein. Immune receptor involved in self-nonself discrimination. In complex with KLRC1 or KLRC2 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia and non-classical MHC class Ib molecules. Enables cytotoxic cells to monitor the expression of MHC class I molecules in healthy cells and to tolerate self. Primarily functions as a ligand binding subunit as it lacks the capacity to signal. 1. Boyington, JC. et al. (1999) Immunity 10, 75-82. PMID: 10023772 2. Bhagat, G. et al. (2008) The Journal of clinical investigation 118, 281-93. PMID: 18064301 3. Sullivan, LC. et al. (2007) Immunity 27, 900-11. PMID: 18083576 4. Lin, Z. et al. (2023) Nature immunology 24, 1087-1097. PMID: 37264229 5. Braud, VM. et al. (1998) Nature 391, 795-9. PMID: 9486650 6. Llano, M. et al. (1998) European journal of immunology 28, 2854-63. PMID: 9754572 7. Jabri, B. et al. (2002) Immunity 17, 487-99. PMID: 12387742 8. Valiante, NM. et al. (1997) Immunity 7, 739-51. PMID: 9430220
Note	For research use only

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Datasheet

Human CD94/KLRD1 Recombinant Protein (C-Fc).pdf

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Human CD94/KLRD1 Recombinant Protein (C-Fc) (HC299011)

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