Anti-CD94/KLRD1 Polyclonal Antibody (HC299014)

Name: Anti-CD94/KLRD1 Polyclonal Antibody
Brand: abinScience
SKU: HC299014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HC299014

Описание

Anti-CD94/KLRD1 Polyclonal Antibody (HC299014) is a rabbit polyclonal antibody detecting KLRD1 in ELISA, IHC, WB. Suitable for Human, Macaca mulatta, Pan troglodytes, and Pongo pygmaeus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human CD94/KLRD1 (Lys32-Ile179).

Цель

Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, Natural killer cells antigen CD94, CD94, KP43, KLRD1

Очистка

Purified by antigen affinity column.

Номер доступа

Q13241

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Natural killer cells antigen CD94 (KLRD1) is a ~20 kDa protein. Immune receptor involved in self-nonself discrimination. In complex with KLRC1 or KLRC2 on cytotoxic and regulatory lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib molecule HLA-E loaded with self-peptides derived from the signal sequence of classical MHC class Ia and non-classical MHC class Ib molecules. Enables cytotoxic cells to monitor the expression of MHC class I molecules in healthy cells and to tolerate self. Primarily functions as a ligand binding subunit as it lacks the capacity to signal.

1. Boyington, JC. et al. (1999) Immunity 10, 75-82. PMID: 10023772

2. Bhagat, G. et al. (2008) The Journal of clinical investigation 118, 281-93. PMID: 18064301

3. Sullivan, LC. et al. (2007) Immunity 27, 900-11. PMID: 18083576

4. Lin, Z. et al. (2023) Nature immunology 24, 1087-1097. PMID: 37264229

5. Braud, VM. et al. (1998) Nature 391, 795-9. PMID: 9486650

6. Llano, M. et al. (1998) European journal of immunology 28, 2854-63. PMID: 9754572

7. Jabri, B. et al. (2002) Immunity 17, 487-99. PMID: 12387742

8. Valiante, NM. et al. (1997) Immunity 7, 739-51. PMID: 9430220

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-CD94/KLRD1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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