

| Número de catálogo | JN878034 | ||||||||
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| Descripción |
Anti-Clostridium perfringens Alpha-toxin/PLC Polyclonal Antibody (JN878034) is a rabbit polyclonal antibody detecting Alpha-toxin. Suitable for Clostridium perfringens.
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| Reactividad de especies | Clostridium perfringens | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Clostridium perfringens Alpha-toxin/PLC (Trp29-Lys398). | ||||||||
| Objetivo | Alpha-toxin, EC:3.1.4.3, Hemolysin, Lecithinase, PLC, Phosphatidylcholine cholinephosphohydrolase, Phospholipase C, cpa, plc | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Pureza | >95% as determined by SDS-PAGE. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9RF12 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Phospholipase C (Alpha-toxin/PLC) is a ~45 kDa protein. Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Constitutes an essential virulence factor in gas gangrene. Binds to eukaryotic membranes where it hydrolyzes both phosphatidylcholine and sphingomyelin, causing cell rupture. The diacylglycerol produced can activate both the arachidonic acid pathway, leading to modulation of the inflammatory response cascade and thrombosis, and protein kinase C, leading to activation of eukaryotic phospholipases and further membrane damage. | ||||||||
| Nota | For research use only |


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