

| Número de catálogo | HY088053 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Rabbit | ||||
| Aplicaciones | ELISA | ||||
| Especie huésped | Human | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | VHH-Fc | ||||
| ID de clon | SAA2585 | ||||
| Objetivo | HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | Q9Y3Q4 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) is a ~129 kDa protein. Hyperpolarization-activated ion channel that are permeable to Na(+) and K(+) ions with very slow activation and inactivation. Exhibits higher selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat (Probable). Contributes to the native pacemaker currents in neurons (Ih) (Probable). May mediate responses to sour stimuli. 1. Ludwig, A. et al. (1999) The EMBO journal 18, 2323-9. PMID: 10228147 2. Seifert, R. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 9391-6. PMID: 10430953 3. Xu, X. et al. (2010) The Journal of biological chemistry 285, 37082-91. PMID: 20829353 4. Milanesi, R. et al. (2006) The New England journal of medicine 354, 151-7. PMID: 16407510 5. Ueda, K. et al. (2009) Journal of human genetics 54, 115-21. PMID: 19165230 | ||||
| Nota | For research use only |
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