

| Número de catálogo | VK665014 | ||||||||
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| Descripción |
Anti-HHV-5/HCMV glycoprotein H/gH Polyclonal Antibody (VK665014) is a rabbit polyclonal antibody detecting HHV-5/HCMV glycoprotein H/gH. Suitable for Human cytomegalovirus.
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| Reactividad de especies | Human cytomegalovirus (HCMV) (HHV-5) (Human herpesvirus 5) | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant HHV-5/HCMV glycoprotein H/gH (Phe298-Val605). | ||||||||
| Objetivo | Envelope glycoprotein H, UL75, gH | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Pureza | >95% as determined by SDS-PAGE. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P12824 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Envelope glycoprotein H (gH) is a ~84 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distinct complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA, and in glioblastoma cells by interacting with host EPHA2. | ||||||||
| Nota | For research use only |




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