InVivoMAb Anti-HCMV/HHV-5 gH/UL75 Antibody (Iv0180) (VK705010)

Name: InVivoMAb Anti-HCMV/HHV-5 gH/UL75 Antibody (Iv0180)
Brand: abinScience
SKU: VK705010
Price: 370 USD
Availability: InStock

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100ug
1mg

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Overview

Catalog No.	VK705010
Description	InVivoMAb Anti-HCMV/HHV5 gH/UL75 Antibody (Iv0180) [Iv0180] (VK705010) is a human monoclonal antibody detecting Envelope glycoprotein H in ELISA, Neutralization.
Species reactivity	Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Applications	ELISA, Neutralization
Host species	Human
Isotype	IgG1, kappa
Clone ID	Iv0180
Clonality	Monoclonal
Target	Envelope glycoprotein H, gH, gH, UL75
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Associated products	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Accession	P12824
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Envelope glycoprotein H (gH/UL75) is a ~84 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distinct complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA, and in glioblastoma cells by interacting with host EPHA2.
Note	For research use only. Not suitable for clinical or therapeutic use.