

| Каталожный номер | VK665014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-HHV-5/HCMV glycoprotein H/gH Polyclonal Antibody (VK665014) is a rabbit polyclonal antibody detecting HHV-5/HCMV glycoprotein H/gH. Suitable for Human cytomegalovirus.
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| Реактивность видов | Human cytomegalovirus (HCMV) (HHV-5) (Human herpesvirus 5) | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant HHV-5/HCMV glycoprotein H/gH (Phe298-Val605). | ||||||||
| Цель | Envelope glycoprotein H, UL75, gH | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Чистота | >95% as determined by SDS-PAGE. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P12824 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Фон | Envelope glycoprotein H (gH) is a ~84 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distinct complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA, and in glioblastoma cells by interacting with host EPHA2. | ||||||||
| Примечание | For research use only |




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