Anti-Human ADAMTS5 Recombinant Antibody (7B4) (HV374023)

Name: Anti-Human ADAMTS5 Recombinant Antibody (7B4)
Brand: abinScience
SKU: HV374023
Price: 191 USD
Availability: InStock

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Цена(USD):

Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HV374023

Реактивность видов

Human

Применения

ELISA, Neutralization

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG1

ID клона

7B4

Цель

ADAMTS5, ADAM-TS 5, ADAM-TS5, ADAMTS-5, ADAMTS11, ADAM-TS 11, ADAMTS-11, ADMP2, ADMP-2, A disintegrin and metalloproteinase with thrombospondin motifs 5, A disintegrin and metalloproteinase with thrombospondin motifs 11, Aggrecanase-2

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Связанные продукты

pH 7.4 Dilution Buffer

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q9UNA0

RRID

Anti-Human ADAMTS5 Antibody (7B4) (abinScience Cat# HV374023, RRID:AB_3725376)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS5) is a ~101 kDa protein. Metalloproteinase that plays an important role in connective tissue organization, development, inflammation and cell migration. Extracellular matrix (ECM) degrading enzyme that show proteolytic activity toward the hyalectan group of chondroitin sulfate proteoglycans (CSPGs) including ACAN, VCAN, BCAN and NCAN. Cleavage within the hyalectans occurs at Glu-Xaa recognition motifs. Plays a role in embryonic development, including limb and cardiac morphogenesis, and skeletal muscle development through its VCAN remodeling properties. Cleaves VCAN in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration.

1. Nakada, M. et al. (2005) Acta neuropathologica 110, 239-46. PMID: 16133547

2. Longpré, JM. et al. (2009) The international journal of biochemistry & cell biology 41, 1116-26. PMID: 18992360

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human ADAMTS5 Antibody (7B4)

Ссылки

Даташит

Anti-Human ADAMTS5 Recombinant Antibody (7B4).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа