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| カタログ番号 | HX089013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1788 | ||||
| ターゲット | CAV, CAV1, Caveolin-1 | ||||
| エンドトキシンレベル | < 10 EU/mg | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q03135 | ||||
| RRID | Anti-Human CAV1/Caveolin-1 Antibody (SAA1788) (abinScience Cat# HX089013, RRID:AB_3727550) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Caveolin-1 (CAV1) is a ~20 kDa protein. May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. 1. Vargas, L. et al. (2002) The Journal of biological chemistry 277, 9351-7. PMID: 11751885 2. McMahon, KA. et al. (2009) The EMBO journal 28, 1001-15. PMID: 19262564 3. Ohnuma, K. et al. (2007) The Journal of biological chemistry 282, 10117-10131. PMID: 17287217 4. Hwangbo, C. et al. (2016) Oncogene 35, 389-401. PMID: 25893292 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human CAV1/Caveolin-1 Antibody (SAA1788)
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