Anti-Human Endoglin/CD105 Recombinant Antibody (SAA0041), APC (HB604137)

Name: Anti-Human Endoglin/CD105 Recombinant Antibody (SAA0041), APC
Brand: abinScience
SKU: HB604137
Price: 290 USD
Availability: InStock

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概要
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参考文献
データシート
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概要

カタログ番号	HB604137
種反応性	Human
アプリケーション	FCM
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
クローンID	SAA0041
抱合	APC
ターゲット	CD105, END, Endoglin, ENG
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	Human IgG1 Recombinant Isotype Control Antibody (HyHEL-10), APC
アクセッション番号	P17813
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. 1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454 2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529 3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484 4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773 5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830 6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366 7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Flow CytoMetry

Flow-cytometry using APC anti-human CD105 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD105 monoclonal antibody (Catalog: HB604137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

参考文献

データシート