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Anti-Human Endoglin/CD105 Monoclonal Antibody (1A609) (HB604015)

Anti-Human Endoglin/CD105 Monoclonal Antibody (1A609)
Anti-Human Endoglin/CD105 Monoclonal Antibody (1A609)
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Vista general
Número de catálogoHB604015
Descripción
Anti-Human CD105/ENG Monoclonal Antibody (1A609) [1A609] (HB604015) is a mouse monoclonal antibody detecting CD105 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG
ID de clon1A609
Inmunógeno E. coli - derived recombinant human CD105/ENG (Thr27-Gly581).
Objetivo Endoglin, CD105, ENG
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P17813
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.

1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454
2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529
3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484
4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773
5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830
6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366
7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410
Nota For research use only.
Imágenes
  • Anti-Human Endoglin/CD105 Monoclonal Antibody (1A609)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD105/ENG Monoclonal Antibody (1A609)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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