Anti-Human Endoglin/CD105 Monoclonal Antibody (1A609) (HB604015)

Name: Anti-Human Endoglin/CD105 Monoclonal Antibody (1A609)
Brand: abinScience
SKU: HB604015
Price: 106 USD
Availability: InStock

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概要

カタログ番号	HB604015
説明	Anti-Human CD105/ENG Monoclonal Antibody (1A609) [1A609] (HB604015) is a mouse monoclonal antibody detecting CD105 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
種反応性	Human
アプリケーション	ELISA, IHC, WB
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG
クローンID	1A609
免疫原	E. coli - derived recombinant human CD105/ENG (Thr27-Gly581).
ターゲット	Endoglin, CD105, ENG
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P17813
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. 1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454 2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529 3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484 4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773 5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830 6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366 7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410
注意事項	For research use only.