Anti-Human Endoglin/CD105 Monoclonal Antibody (1A609) (HB604015)

Name: Anti-Human Endoglin/CD105 Monoclonal Antibody (1A609)
Brand: abinScience
SKU: HB604015
Price: 106 USD
Availability: InStock

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Каталожный номер	HB604015
Описание	Anti-Human CD105/ENG Monoclonal Antibody (1A609) [1A609] (HB604015) is a mouse monoclonal antibody detecting CD105 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Реактивность видов	Human
Применения	ELISA, IHC, WB
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG
ID клона	1A609
Иммуноген	E. coli - derived recombinant human CD105/ENG (Thr27-Gly581).
Цель	Endoglin, CD105, ENG
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P17813
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. 1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454 2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529 3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484 4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773 5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830 6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366 7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410
Примечание	For research use only.