Anti-Human Nectin-2/CD112 Recombinant Antibody (SAA2364) (HV456013)

Name: Anti-Human Nectin-2/CD112 Recombinant Antibody (SAA2364)
Brand: abinScience
SKU: HV456013
Price: 126 USD
Availability: InStock

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20ug
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1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HV456013

Reactivité des espèces

Human

Applications

ELISA, FCM

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA2364

Cible

Nectin-2, Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Nectin cell adhesion molecule 2, Poliovirus receptor-related protein 2, CD112, NECTIN2, HVEB, PRR2, PVRL2

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q92692

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.

1. Zhu, Y. et al. (2016) The Journal of experimental medicine 213, 167-76. PMID: 26755705

2. Warner, MS. et al. (1998) Virology 246, 179-89. PMID: 9657005

Note

For research use only

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Images

SDS-PAGE

SDS-PAGE for Anti-Human CD112/Nectin-2/PVRL2 Antibody (SAA2364)
Bioactivity

Detects recombinant human CD112 (Catalog No: HV456011) in indirect ELISA