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Anti-Human Nectin-2/CD112 Recombinant Nanobody (SAA2116) (HV456023)

Anti-Human Nectin-2/CD112 Recombinant Nanobody (SAA2116)
Anti-Human Nectin-2/CD112 Recombinant Nanobody (SAA2116)
Anti-Human Nectin-2/CD112 Recombinant Nanobody (SAA2116)
Anti-Human Nectin-2/CD112 Recombinant Nanobody (SAA2116)
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Aperçu
Numéro de catalogueHV456023
Description
Anti-Human CD112/Nectin-2/PVRL2 Nanobody (SAA2116) [SAA2116] (HV456023) is a alpaca monoclonal antibody detecting Nectin-2 in ELISA. Suitable for Human.
Reactivité des espècesHuman
ApplicationsELISA
Espèce hôteAlpaca
ClonalitéMonoclonal
IsotypeVHH-8His-Cys-tag
ID de cloneSAA2116
Cible NECTIN2, HVEB, PRR2, PVRL2, Nectin-2, CD112, Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Nectin cell adhesion molecule 2 receptor-related protein 2
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Purified by Nickel column.
Numéro d'accès Q92692
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Nectin-2 (CD112/PVRL2) is a ~57 kDa protein. Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.

1. Zhu, Y. et al. (2016) The Journal of experimental medicine 213, 167-76. PMID: 26755705
2. Warner, MS. et al. (1998) Virology 246, 179-89. PMID: 9657005
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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