Anti-Human EMMPRIN/CD147 Recombinant Antibody (4A5) (HW664023)

Name: Anti-Human EMMPRIN/CD147 Recombinant Antibody (4A5)
Brand: abinScience
SKU: HW664023
Price: 110 USD
Availability: InStock

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20ug
50ug
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1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HW664023

Reactivité des espèces

Human

Applications

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

4A5

Applications testées

WB, FCM

Cible

Hepatoma-associated antigen, BSG, HAb18G, 5F7, TCSF, OK blood group antigen, Collagenase stimulatory factor, CD147, Leukocyte activation antigen M6, Basigin, Extracellular matrix metalloproteinase inducer, EMMPRIN, Tumor cell-derived collagenase stimulatory factor

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P35613

RRID

Anti-Human CD147/BSG Antibody (4A5) (abinScience Cat# HW664023, RRID:AB_3728962)
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Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Basigin (CD147/BSG) is a ~42 kDa protein. Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes.

1. Aït-Ali, N. et al. (2015) Cell 161, 817-32. PMID: 25957687

2. Redzic, JS. et al. (2011) Journal of molecular biology 411, 68-82. PMID: 21620857

Note

For research use only.

Isotype Control

Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173) (MF533507)
Mouse IgG2a Recombinant Isotype Control Antibody (S43.10) (MF533307)

Images

Bioactivity

Detects Human CD147/BSG in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Anti-Human CD147/BSG Antibody (4A5).
Flow CytoMetry

Flow-cytometry using FITC anti-human CD147 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD147 monoclonal antibody (Catalog: HW664023, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-CD147/BSG monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human CD147/BSG (Catalog No: HW664011)