

| Numéro de catalogue | HC363117 |
|---|---|
| Reactivité des espèces | Human |
| Applications | FCM |
| Espèce hôte | Mouse |
| Clonalité | Monoclonal |
| Isotype | IgG1, kappa |
| ID de clone | AB-2 |
| Conjugaison | FITC |
| Cible | HPTP eta, R-PTP-J, Protein-tyrosine phosphatase eta, Density-enhanced phosphatase 1, Receptor-type tyrosine-protein phosphatase eta, Protein-tyrosine phosphatase receptor type J, DEP-1, R-PTP-eta, CD148, PTPRJ, DEP1 |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Produits associés | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), FITC |
| Numéro d'accès | Q12913 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Contexte | Receptor-type tyrosine-protein phosphatase eta (CD148/PTPRJ) is a ~145 kDa protein. Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Has a role in megakaryocytes and platelet formation. Involved in vascular development. Regulator of macrophage adhesion and spreading. 1. Kovalenko, M. et al. (2000) The Journal of biological chemistry 275, 16219-26. PMID: 10821867 2. Persson, C. et al. (2002) FEBS letters 517, 27-31. PMID: 12062403 3. Holsinger, LJ. et al. (2002) Oncogene 21, 7067-76. PMID: 12370829 4. Palka, HL. et al. (2003) The Journal of biological chemistry 278, 5728-35. PMID: 12475979 5. Tsuboi, N. et al. (2008) The Biochemical journal 413, 193-200. PMID: 18348712 6. Sacco, F. et al. (2009) The Journal of biological chemistry 284, 22048-22058. PMID: 19494114 7. Omerovic, J. et al. (2010) The Biochemical journal 426, 65-72. PMID: 19922411 8. Arora, D. et al. (2011) The Journal of biological chemistry 286, 10918-29. PMID: 21262971 9. Kellie, S. et al. (2004) Journal of cell science 117, 609-18. PMID: 14709717 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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