

| Catalog No. | HC363127 |
|---|---|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Mouse |
| Isotype | IgG1, kappa |
| Clone ID | AB-2 |
| Conjugation | PE |
| Clonality | Monoclonal |
| Target | HPTP eta, R-PTP-J, Protein-tyrosine phosphatase eta, Density-enhanced phosphatase 1, Receptor-type tyrosine-protein phosphatase eta, Protein-tyrosine phosphatase receptor type J, DEP-1, R-PTP-eta, CD148, PTPRJ, DEP1 |
| Endotoxin level | Please contact with the lab for this information. |
| Associated products | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PE |
| Accession | Q12913 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | Receptor-type tyrosine-protein phosphatase eta (CD148/PTPRJ) is a ~145 kDa protein. Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Has a role in megakaryocytes and platelet formation. Involved in vascular development. Regulator of macrophage adhesion and spreading. 1. Kovalenko, M. et al. (2000) The Journal of biological chemistry 275, 16219-26. PMID: 10821867 2. Persson, C. et al. (2002) FEBS letters 517, 27-31. PMID: 12062403 3. Holsinger, LJ. et al. (2002) Oncogene 21, 7067-76. PMID: 12370829 4. Palka, HL. et al. (2003) The Journal of biological chemistry 278, 5728-35. PMID: 12475979 5. Tsuboi, N. et al. (2008) The Biochemical journal 413, 193-200. PMID: 18348712 6. Sacco, F. et al. (2009) The Journal of biological chemistry 284, 22048-22058. PMID: 19494114 7. Omerovic, J. et al. (2010) The Biochemical journal 426, 65-72. PMID: 19922411 8. Arora, D. et al. (2011) The Journal of biological chemistry 286, 10918-29. PMID: 21262971 9. Kellie, S. et al. (2004) Journal of cell science 117, 609-18. PMID: 14709717 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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