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Anti-Human CD148 Recombinant Antibody (AB-2) (HC363107)

Anti-Human CD148 Recombinant Antibody (AB-2)
Anti-Human CD148 Recombinant Antibody (AB-2)
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Overview
Catalog No.HC363107
Species reactivityHuman
ApplicationsFCM
Host speciesMouse
IsotypeIgG1, kappa
Clone IDAB-2
Clonality Monoclonal
Target HPTP eta, R-PTP-J, Protein-tyrosine phosphatase eta, Density-enhanced phosphatase 1, Receptor-type tyrosine-protein phosphatase eta, Protein-tyrosine phosphatase receptor type J, DEP-1, R-PTP-eta, CD148, PTPRJ, DEP1
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q12913
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Receptor-type tyrosine-protein phosphatase eta (CD148/PTPRJ) is a ~145 kDa protein. Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Has a role in megakaryocytes and platelet formation. Involved in vascular development. Regulator of macrophage adhesion and spreading.

1. Kovalenko, M. et al. (2000) The Journal of biological chemistry 275, 16219-26. PMID: 10821867
2. Persson, C. et al. (2002) FEBS letters 517, 27-31. PMID: 12062403
3. Holsinger, LJ. et al. (2002) Oncogene 21, 7067-76. PMID: 12370829
4. Palka, HL. et al. (2003) The Journal of biological chemistry 278, 5728-35. PMID: 12475979
5. Tsuboi, N. et al. (2008) The Biochemical journal 413, 193-200. PMID: 18348712
6. Sacco, F. et al. (2009) The Journal of biological chemistry 284, 22048-22058. PMID: 19494114
7. Omerovic, J. et al. (2010) The Biochemical journal 426, 65-72. PMID: 19922411
8. Arora, D. et al. (2011) The Journal of biological chemistry 286, 10918-29. PMID: 21262971
9. Kellie, S. et al. (2004) Journal of cell science 117, 609-18. PMID: 14709717
Note For research use only.
Images
  • Anti-Human CD148 Recombinant Antibody (AB-2)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD148 Antibody (AB-2)

References
Formula
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