

| Catalog No. | HC363107 |
|---|---|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Mouse |
| Isotype | IgG1, kappa |
| Clone ID | AB-2 |
| Clonality | Monoclonal |
| Target | HPTP eta, R-PTP-J, Protein-tyrosine phosphatase eta, Density-enhanced phosphatase 1, Receptor-type tyrosine-protein phosphatase eta, Protein-tyrosine phosphatase receptor type J, DEP-1, R-PTP-eta, CD148, PTPRJ, DEP1 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | Q12913 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Receptor-type tyrosine-protein phosphatase eta (CD148/PTPRJ) is a ~145 kDa protein. Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, FLT3, PDGFRB, MET, KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Has a role in megakaryocytes and platelet formation. Involved in vascular development. Regulator of macrophage adhesion and spreading. 1. Kovalenko, M. et al. (2000) The Journal of biological chemistry 275, 16219-26. PMID: 10821867 2. Persson, C. et al. (2002) FEBS letters 517, 27-31. PMID: 12062403 3. Holsinger, LJ. et al. (2002) Oncogene 21, 7067-76. PMID: 12370829 4. Palka, HL. et al. (2003) The Journal of biological chemistry 278, 5728-35. PMID: 12475979 5. Tsuboi, N. et al. (2008) The Biochemical journal 413, 193-200. PMID: 18348712 6. Sacco, F. et al. (2009) The Journal of biological chemistry 284, 22048-22058. PMID: 19494114 7. Omerovic, J. et al. (2010) The Biochemical journal 426, 65-72. PMID: 19922411 8. Arora, D. et al. (2011) The Journal of biological chemistry 286, 10918-29. PMID: 21262971 9. Kellie, S. et al. (2004) Journal of cell science 117, 609-18. PMID: 14709717 |
| Note | For research use only. |

SDS-PAGE for Anti-Human CD148 Antibody (AB-2)




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