Anti-Human CD158k/KIR3DL2 Recombinant Antibody (SAA0064), APC (HW633137)

Name: Anti-Human CD158k/KIR3DL2 Recombinant Antibody (SAA0064), APC
Brand: abinScience
SKU: HW633137
Price: 290 USD
Availability: InStock

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概要
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データシート
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概要

カタログ番号	HW633137
種反応性	Human
アプリケーション	FCM
宿主種	Mouse
クローン性	Monoclonal
アイソタイプ	IgG1, kappa
クローンID	SAA0064
抱合	APC
ターゲット	CD158K, MHC class I NK cell receptor, NKAT4, Natural killer-associated transcript 4, KIR3DL2, p70 NK receptor CL-5, CD158k, p70 natural killer cell receptor clone CL-5, CD158 antigen-like family member K, Killer cell immunoglobulin-like receptor 3DL2, NKAT-4
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
アクセッション番号	P43630
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Killer cell immunoglobulin-like receptor 3DL2 (CD158k/KIR3DL2) is a ~50 kDa protein. Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. 1. Goodridge, JP. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 191, 3553-62. PMID: 24018270 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 3. Song, S. et al. (2016) Nature medicine 22, 397-403. PMID: 26928464
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Flow Cytometry

Flow-cytometry using APC anti-human CD158k antibody. Untransfected (Blue Histogram) or Transfected 293T cells (Red Histogram) were stained with an APC anti-human CD158k antibody monoclonal antibody (Catalog # HW633137) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry APC using anti-human CD158k antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human CD158k monoclonal antibody (Catalog: HW633137) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.