

| Catalog No. | HW633147 |
|---|---|
| Description |
Anti-Human CD158k/KIR3DL2 Antibody (SAA0064), PerCP [SAA0064] (HW633147) is a mouse monoclonal antibody detecting KIR3DL2 in FCM. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Mouse |
| Isotype | IgG1, kappa |
| Clone ID | SAA0064 |
| Conjugation | PerCP |
| Clonality | Monoclonal |
| Target | CD158K, MHC class I NK cell receptor, NKAT4, Natural killer-associated transcript 4, KIR3DL2, p70 NK receptor CL-5, CD158k, p70 natural killer cell receptor clone CL-5, CD158 antigen-like family member K, Killer cell immunoglobulin-like receptor 3DL2, NKAT-4 |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | P43630 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | Killer cell immunoglobulin-like receptor 3DL2 (CD158k/KIR3DL2) is a ~50 kDa protein. Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. 1. Goodridge, JP. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 191, 3553-62. PMID: 24018270 2. Dulberger, CL. et al. (2017) Immunity 46, 1018-1029.e7. PMID: 28636952 3. Song, S. et al. (2016) Nature medicine 22, 397-403. PMID: 26928464 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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