Please ensure Javascript is enabled for purposes of website accessibility
Contactez-nous Contactez-nous
FR
Accueil > Products > Anticorps > Anticorps Primaires

Anti-Human CD169/SIGLEC1 Polyclonal Antibody (HV234014)

Fiche technique Partager le produit Copier les informations
Prix(USD) : --
Spécification :
  • 50ug
  • 100ug
Nombre :
Contactez-nous

  • Aperçu

  • Images

  • Reférences

  • Fiche technique

  • SDS

Aperçu
Numéro de catalogueHV234014
Description
Anti-Human CD169/SIGLEC1 Polyclonal Antibody (HV234014) is a rabbit polyclonal antibody detecting CD169/SIGLEC1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human CD169/SIGLEC1 (Gly34-Gly240).
Cible Siglec-1, CD169, SIGLEC1, SN, Sialic acid-binding Ig-like lectin 1, Sialoadhesin
Purification Purified by antigen affinity column.
Numéro d'accès Q9BZZ2
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Sialoadhesin (CD169/SIGLEC1) is a ~182 kDa protein. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Plays a crucial role in limiting bacterial dissemination by engaging sialylated bacteria to promote effective phagocytosis and antigen presentation for the adaptive immune response. Mediates the uptake of various enveloped viruses via sialic acid recognition and subsequently induces the formation of intracellular compartments filled with virions (VCCs). In turn, enhances macrophage-to-T-cell transmission of several viruses including HIV-1 or SARS-CoV-2. Acts as an endocytic receptor mediating clathrin dependent endocytosis.

1. Jones, C. et al. (2003) Molecular microbiology 49, 1213-25. PMID: 12940982
2. Benet, S. et al. (2021) Journal of extracellular vesicles 10, e12046. PMID: 33489013
3. Hammonds, JE. et al. (2017) PLoS pathogens 13, e1006181. PMID: 28129379
4. Perez-Zsolt, D. et al. (2021) Cellular & molecular immunology 18, 2676-2678. PMID: 34782760
5. Zheng, Q. et al. (2015) Cell research 25, 1121-36. PMID: 26358190
Note For research use only.
Images
Reférences
Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.

Courrier : [email protected]

Liste des distributeurs

Obtenir un devis gratuit
Anti-Human CD169/SIGLEC1 Polyclonal Antibody

Accès rapide

Contactez-nous

  • +86-027-65523339

  • [email protected]

  • Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine

  • linkedin
  • Ins
  • youtube
  • youtube
Droit d'auteur © 2026 abinScience. Tous droits réservés. Tous les produits sont uniquement à usage de recherche