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Anti-Human L1CAM Recombinant Antibody (OV52.24) (HB159107)

Anti-Human L1CAM Recombinant Antibody (OV52.24)
Anti-Human L1CAM Recombinant Antibody (OV52.24)
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概要
カタログ番号HB159107
種反応性Human
アプリケーションFCM
宿主種Mouse
クローン性Monoclonal
アイソタイプIgG1, kappa
クローンIDOV52.24
ターゲット CAML1, Neural cell adhesion molecule L1, NCAM-L1, N-CAM-L1, CD171, MIC5, L1CAM
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P32004
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Neural cell adhesion molecule L1 (CD171/L1CAM) is a ~140 kDa protein. Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.

参考文献 1. Chen K, et al. mRNA Vaccines Against SARS-CoV-2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids. Adv Funct Mater. 2022 Sep 26;32(39):2204692. [HB159107]
注意事項 For research use only.
イメージ
  • Anti-Human L1CAM Recombinant Antibody (OV52.24)

    Flow Cytometry

    Flow-cytometry using anti-human CD171 antibody.HeLa cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD171 antibody monoclonal antibody (Catalog # HB159107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献
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