Anti-Human L1CAM Reference Antibody (JCAR023, RUO) (HB159016)

Name: Anti-Human L1CAM Reference Antibody (JCAR023, RUO)
Brand: abinScience
SKU: HB159016
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HB159016
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	JCAR023
Expression system	Mammalian cells
Clonality	Monoclonal
Target	CAML1, Neural cell adhesion molecule L1, NCAM-L1, N-CAM-L1, CD171, MIC5, L1CAM
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P32004
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	JCAR023
Background	Neural cell adhesion molecule L1 (CD171/L1CAM) is a ~140 kDa protein. Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.
References	1. Chen K, et al. mRNA Vaccines Against SARS-CoV-2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids. Adv Funct Mater. 2022 Sep 26;32(39):2204692. [HB159016]
Note	For research use only. Not suitable for clinical or therapeutic use.