Anti-Human L1CAM Recombinant Antibody (OV52.24) (HB159107)

Name: Anti-Human L1CAM Recombinant Antibody (OV52.24)
Brand: abinScience
SKU: HB159107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HB159107
Description	Anti-Human L1CAM Recombinant Antibody (OV52.24) (HB159107) is a mouse monoclonal antibody detecting L1CAM in FCM. Suitable for Human. Highlights ●Affinity Purified — Minimal background and high purity for reliable results.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG1, kappa
Clone ID	OV52.24
Target	CAML1, Neural cell adhesion molecule L1, NCAM-L1, N-CAM-L1, CD171, MIC5, L1CAM
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P32004
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Neural cell adhesion molecule L1 (CD171/L1CAM) is a ~140 kDa protein. Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors. During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.
References	1. Chen K, et al. mRNA Vaccines Against SARS-CoV-2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids. Adv Funct Mater. 2022 Sep 26;32(39):2204692. [HB159107]
Note	For research use only.

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Flow Cytometry

Flow-cytometry using anti-human CD171 antibody.HeLa cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD171 antibody monoclonal antibody (Catalog # HB159107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet

Anti-Human L1CAM Recombinant Antibody (OV52.24).pdf

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Anti-Human L1CAM Recombinant Antibody (OV52.24) (HB159107)

Overview

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References

Datasheet

SDS