Anti-Human CD178/FASLG/TNFSF6 Recombinant Antibody (NOK2/NOK-2), APC (HW497137)

Name: Anti-Human CD178/FASLG/TNFSF6 Recombinant Antibody (NOK2/NOK-2), APC
Brand: abinScience
SKU: HW497137
Price: 290 USD
Availability: InStock

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Каталожный номер	HW497137
Реактивность видов	Human
Применения	FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG2a, kappa
ID клона	NOK2/NOK-2
Конъюгация	APC
Цель	Receptor-binding FasL ectodomain, APL, APT1LG1, FasL ICD, Fas antigen ligand, CD178, sFasL, CD95L, APTL, TNFSF6, Apoptosis antigen ligand, SPA, FASLG, FasL, SPPL2A-processed FasL form, Tumor necrosis factor ligand superfamily member 6, Soluble Fas ligand, Fas ligand, CD95 ligand, CD95-L, FASL
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
Номер доступа	P48023
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Tumor necrosis factor ligand superfamily member 6 (CD178/FASLG) is a ~31 kDa protein. Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis also has a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. 1. Ruiz-García, R. et al. (2015) Pediatric research 78, 603-8. PMID: 26334989 2. Schneider, P. et al. (1997) The Journal of biological chemistry 272, 18827-33. PMID: 9228058 3. Alderson, MR. et al. (1995) The Journal of experimental medicine 181, 71-7. PMID: 7528780 4. Tanaka, M. et al. (1998) Nature medicine 4, 31-6. PMID: 9427603 5. Liu, W. et al. (2016) Structure (London, England : 1993) 24, 2016-2023. PMID: 27806260
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.