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Anti-Human CCR5 Recombinant Antibody (PRO-140), FITC (HW412117)

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Vista general
Número de catálogoHW412117
Reactividad de especiesHuman
AplicacionesFCM
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG4, kappa
ID de clonPRO-140
ConjugaciónFITC
Objetivo C-C CKR-5, CC-CKR-5, CMKBR5, HIV-1 fusion coreceptor, CHEMR13, CCR5, C-C chemokine receptor type 5, CD195, CCR-5
Nivel de endotoxinas Please contact with the lab for this information.
Productos asociados Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4), FITC
Número de acceso P51681
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo

C-C chemokine receptor type 5 (CD195/CCR5) is a ~40 kDa protein. Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.

1. Sharapova, TN. et al. (2018) Acta naturae 10, 115-120. PMID: 30713770
Nota For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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