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Anti-Human IL-17RA/IL-17R Recombinant Antibody (SAA0071), APC (HV263137)

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Aperçu
Numéro de catalogueHV263137
Reactivité des espècesHuman
ApplicationsFCM
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG2, kappa
ID de cloneSAA0071
ConjugaisonAPC
Cible IL17R, CDw217, IL-17RA, Interleukin-17 receptor A, IL-17 receptor A, IL17RA, CD217
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), APC
Numéro d'accès Q96F46
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Interleukin-17 receptor A (CD217/IL17RA) is a ~96 kDa protein. Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Receptor for IL17A. Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F. Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC.

1. Kuestner, RE. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 179, 5462-73. PMID: 17911633
2. Yao, Z. et al. (1997) Cytokine 9, 794-800. PMID: 9367539
3. Ely, LK. et al. (2009) Nature immunology 10, 1245-51. PMID: 19838198
4. Toy, D. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 36-9. PMID: 16785495
5. Wright, JF. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 2799-805. PMID: 18684971
6. Puel, A. et al. (2011) Science (New York, N.Y.) 332, 65-8. PMID: 21350122
7. Boisson, B. et al. (2013) Immunity 39, 676-86. PMID: 24120361
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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