Anti-Human IL-17RA/IL-17R Reference Antibody (OSE-703, RUO) (HV263036)

Name: Anti-Human IL-17RA/IL-17R Reference Antibody (OSE-703, RUO)
Brand: abinScience
SKU: HV263036
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HV263036
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	OSE-703
Expression system	Mammalian cells
Clonality	Monoclonal
Target	IL17R, CDw217, IL-17RA, Interleukin-17 receptor A, IL-17 receptor A, IL17RA, CD217
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q96F46
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	OSE-703, OSE703, OSE703
Background	Interleukin-17 receptor A (CD217/IL17RA) is a ~96 kDa protein. Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Receptor for IL17A. Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F. Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC. 1. Kuestner, RE. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 179, 5462-73. PMID: 17911633 2. Yao, Z. et al. (1997) Cytokine 9, 794-800. PMID: 9367539 3. Ely, LK. et al. (2009) Nature immunology 10, 1245-51. PMID: 19838198 4. Toy, D. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 36-9. PMID: 16785495 5. Wright, JF. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 2799-805. PMID: 18684971 6. Puel, A. et al. (2011) Science (New York, N.Y.) 332, 65-8. PMID: 21350122 7. Boisson, B. et al. (2013) Immunity 39, 676-86. PMID: 24120361
References	1. https://synapse.zhihuiya.com/drug/821efdfc6c6d493eaaa73bea8ca9f862 [HV263036]
Note	For research use only. Not suitable for clinical or therapeutic use.