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Anti-Human CD217/IL17RA Recombinant Antibody (SAA0071), FITC (HV263117)

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Overview
Catalog No.HV263117
Species reactivityHuman
ApplicationsFCM
Host speciesHuman
IsotypeIgG2, kappa
Clone IDSAA0071
ConjugationFITC
Clonality Monoclonal
Target IL17R, CDw217, IL-17RA, Interleukin-17 receptor A, IL-17 receptor A, IL17RA, CD217
Endotoxin level Please contact with the lab for this information.
Associated products Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), FITC
Accession Q96F46
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

Interleukin-17 receptor A (CD217/IL17RA) is a ~96 kDa protein. Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Receptor for IL17A. Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F. Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC.

1. Kuestner, RE. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 179, 5462-73. PMID: 17911633
2. Yao, Z. et al. (1997) Cytokine 9, 794-800. PMID: 9367539
3. Ely, LK. et al. (2009) Nature immunology 10, 1245-51. PMID: 19838198
4. Toy, D. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 36-9. PMID: 16785495
5. Wright, JF. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 2799-805. PMID: 18684971
6. Puel, A. et al. (2011) Science (New York, N.Y.) 332, 65-8. PMID: 21350122
7. Boisson, B. et al. (2013) Immunity 39, 676-86. PMID: 24120361
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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