Anti-Human IL-17RA/IL-17R Recombinant Antibody (SAA0071) (HV263107)

Name: Anti-Human IL-17RA/IL-17R Recombinant Antibody (SAA0071)
Brand: abinScience
SKU: HV263107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HV263107
Species reactivity	Human
Applications	FCM
Host species	Human
Isotype	IgG2, kappa
Clone ID	SAA0071
Clonality	Monoclonal
Target	IL17R, CDw217, IL-17RA, Interleukin-17 receptor A, IL-17 receptor A, IL17RA, CD217
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q96F46
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Interleukin-17 receptor A (CD217/IL17RA) is a ~96 kDa protein. Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Receptor for IL17A. Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F. Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC. 1. Kuestner, RE. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 179, 5462-73. PMID: 17911633 2. Yao, Z. et al. (1997) Cytokine 9, 794-800. PMID: 9367539 3. Ely, LK. et al. (2009) Nature immunology 10, 1245-51. PMID: 19838198 4. Toy, D. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 36-9. PMID: 16785495 5. Wright, JF. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 2799-805. PMID: 18684971 6. Puel, A. et al. (2011) Science (New York, N.Y.) 332, 65-8. PMID: 21350122 7. Boisson, B. et al. (2013) Immunity 39, 676-86. PMID: 24120361
Note	For research use only.