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| カタログ番号 | HV263137 |
|---|---|
| 種反応性 | Human |
| アプリケーション | FCM |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2, kappa |
| クローンID | SAA0071 |
| 抱合 | APC |
| ターゲット | IL17R, CDw217, IL-17RA, Interleukin-17 receptor A, IL-17 receptor A, IL17RA, CD217 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 関連製品 | Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), APC |
| アクセッション番号 | Q96F46 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Interleukin-17 receptor A (CD217/IL17RA) is a ~96 kDa protein. Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. Receptor for IL17A. Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F. Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC. 1. Kuestner, RE. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 179, 5462-73. PMID: 17911633 2. Yao, Z. et al. (1997) Cytokine 9, 794-800. PMID: 9367539 3. Ely, LK. et al. (2009) Nature immunology 10, 1245-51. PMID: 19838198 4. Toy, D. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 36-9. PMID: 16785495 5. Wright, JF. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 2799-805. PMID: 18684971 6. Puel, A. et al. (2011) Science (New York, N.Y.) 332, 65-8. PMID: 21350122 7. Boisson, B. et al. (2013) Immunity 39, 676-86. PMID: 24120361 |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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