Anti-Human TRAILR1/TNFRSF10A Recombinant Antibody (SAA0083) (HT017107)

Name: Anti-Human TRAILR1/TNFRSF10A Recombinant Antibody (SAA0083)
Brand: abinScience
SKU: HT017107
Price: 191 USD
Availability: InStock

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Vista general

Número de catálogo	HT017107
Reactividad de especies	Human
Aplicaciones	FCM
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG1
ID de clon	SAA0083
Objetivo	TNF-related apoptosis-inducing ligand receptor 1, APO2, Death receptor 4, TRAIL receptor 1, TRAIL-R1, CD261, DR4, TRAILR1, TNFRSF10A, Tumor necrosis factor receptor superfamily member 10A
Nivel de endotoxinas	< 10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	O00220
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Tumor necrosis factor receptor superfamily member 10A (CD261/TNFRSF10A) is a ~50 kDa protein. Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. 1. Ramamurthy, V. et al. (2015) Acta crystallographica. Section F, Structural biology communications 71, 1273-81. PMID: 26457518 2. Chyuan, IT. et al. (2024) Journal of biomedical science 31, 33. PMID: 38532423 3. Rossin, A. et al. (2009) The Biochemical journal 419, 185-92, 2 p following 192. PMID: 19090789 4. Chaudhary, PM. et al. (1997) Immunity 7, 821-30. PMID: 9430227
Nota	For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human CD261/TNFRSF10A/DR4 Antibody (SAA0083)

Referencias

Datasheet

Anti-Human TRAILR1/TNFRSF10A Recombinant Antibody (SAA0083).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

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Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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