Anti-Human TRAILR1/TNFRSF10A Recombinant Antibody (SAA0083), APC (HT017137)

Name: Anti-Human TRAILR1/TNFRSF10A Recombinant Antibody (SAA0083), APC
Brand: abinScience
SKU: HT017137
Price: 290 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD): --

Spec:

50T
100T

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.	HT017137
Description	Anti-Human TRAILR1/TNFRSF10A Recombinant Antibody (SAA0083), APC (HT017137) is a human monoclonal antibody detecting TRAILR1/TNFRSF10A in FCM. Suitable for Human. Highlights ●APC Conjugated — Ready for direct detection without secondary antibody.
Species reactivity	Human
Applications	FCM
Host species	Human
Clonality	Monoclonal
Isotype	IgG1
Clone ID	SAA0083
Conjugation	APC
Target	TNF-related apoptosis-inducing ligand receptor 1, APO2, Death receptor 4, TRAIL receptor 1, TRAIL-R1, CD261, DR4, TRAILR1, TNFRSF10A, Tumor necrosis factor receptor superfamily member 10A
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Associated products	Human IgG1 kappa Recombinant Isotype Control Antibody (HyHEL-10), APC
Accession	O00220
Form	Liquid
Storage buffer	0.01M PBS pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Tumor necrosis factor receptor superfamily member 10A (CD261/TNFRSF10A) is a ~50 kDa protein. Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. 1. Ramamurthy, V. et al. (2015) Acta crystallographica. Section F, Structural biology communications 71, 1273-81. PMID: 26457518 2. Chyuan, IT. et al. (2024) Journal of biomedical science 31, 33. PMID: 38532423 3. Rossin, A. et al. (2009) The Biochemical journal 419, 185-92, 2 p following 192. PMID: 19090789 4. Chaudhary, PM. et al. (1997) Immunity 7, 821-30. PMID: 9430227
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Images

References

Datasheet

Anti-Human TRAILR1/TNFRSF10A Recombinant Antibody (SAA0083), APC.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human TRAILR1/TNFRSF10A Recombinant Antibody (SAA0083), APC (HT017137)

Overview

Images

References

Datasheet

SDS