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| カタログ番号 | HV400013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1721 | ||||
| ターゲット | Inhibitory receptor protein 60, IRp60, CMRF35-H, CLM-8, CMRF35-H9, CMRF35-like molecule 8, CD300A, NK inhibitory receptor, IgSF12, CD300a, CMRF35H, IRC1/IRC2, IGSF12, CD300 antigen-like family member A, CMRF-35-H9, Immunoglobulin superfamily member 12 | ||||
| エンドトキシンレベル | < 10 EU/mg | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9UGN4 | ||||
| RRID | Anti-Human CD300a Antibody (SAA1721) (abinScience Cat# HV400013, RRID:AB_3727482) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | CMRF35-like molecule 8 (CD300a) is a ~33 kDa protein. Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6. 1. Clark, GJ. et al. (2000) Tissue antigens 55, 101-9. PMID: 10746781 2. Bachelet, I. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7989-95. PMID: 16339535 3. Green, BJ. et al. (1998) International immunology 10, 891-9. PMID: 9701027 4. Kim, EJ. et al. (2012) Immunology 135, 226-35. PMID: 22043923 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human CD300a Antibody (SAA1721)
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