

| Numéro de catalogue | HX118107 |
|---|---|
| Reactivité des espèces | Human, Mouse |
| Applications | FCM |
| Espèce hôte | Mouse |
| Clonalité | Monoclonal |
| Isotype | IgG1, kappa |
| ID de clone | B70 |
| Cible | JAG1, Jagged1, CD339, JAGL1, Protein jagged-1, hJ1 |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | P78504 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Contexte | Protein jagged-1 (CD339/JAG1) is a ~133 kDa protein. Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). 1. Cordle, J. et al. (2008) Nature structural & molecular biology 15, 849-57. PMID: 18660822 2. Bauer, RC. et al. (2010) Human mutation 31, 594-601. PMID: 20437614 3. Li, L. et al. (1998) Immunity 8, 43-55. PMID: 9462510 |
| Note | For research use only. |

Detects CD339/JAG1 in indirect ELISAs.




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