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Anti-Human CD339/JAG1 Recombinant Antibody (B70), PerCP (HX118147)

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Overview
Catalog No.HX118147
Species reactivityHuman, Mouse
ApplicationsFCM
Host speciesMouse
IsotypeIgG1, kappa
Clone IDB70
ConjugationPerCP
Clonality Monoclonal
Target JAG1, Jagged1, CD339, JAGL1, Protein jagged-1, hJ1
Endotoxin level Please contact with the lab for this information.
Associated products Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), PerCP
Accession P78504
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Store at 4°C for 12 months. Protect from light. Do not freeze.
Background

Protein jagged-1 (CD339/JAG1) is a ~133 kDa protein. Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro).

1. Cordle, J. et al. (2008) Nature structural & molecular biology 15, 849-57. PMID: 18660822
2. Bauer, RC. et al. (2010) Human mutation 31, 594-601. PMID: 20437614
3. Li, L. et al. (1998) Immunity 8, 43-55. PMID: 9462510
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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