

| Catalog No. | HX118107 |
|---|---|
| Species reactivity | Human, Mouse |
| Applications | FCM |
| Host species | Mouse |
| Isotype | IgG1, kappa |
| Clone ID | B70 |
| Clonality | Monoclonal |
| Target | JAG1, Jagged1, CD339, JAGL1, Protein jagged-1, hJ1 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P78504 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Protein jagged-1 (CD339/JAG1) is a ~133 kDa protein. Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). 1. Cordle, J. et al. (2008) Nature structural & molecular biology 15, 849-57. PMID: 18660822 2. Bauer, RC. et al. (2010) Human mutation 31, 594-601. PMID: 20437614 3. Li, L. et al. (1998) Immunity 8, 43-55. PMID: 9462510 |
| Note | For research use only. |

Detects CD339/JAG1 in indirect ELISAs.




Contact us for custom quotes, bulk requests and any other issues.
Mail: support@abinScience.com


+86-27-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский