Anti-Human CD55/DAF Recombinant Antibody (SAA0839), APC (HY307237)

Name: Anti-Human CD55/DAF Recombinant Antibody (SAA0839), APC
Brand: abinScience
SKU: HY307237
Price: 290 USD
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Número de catálogo	HY307237
Reactividad de especies	Human
Aplicaciones	ELISA, FCM, WB
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a
ID de clon	SAA0839
Conjugación	APC
Objetivo	Complement decay-accelerating factor, CR, DAF, CD55
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), APC
Número de acceso	P08174
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Complement decay-accelerating factor (CD55) is a ~41 kDa protein. This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage. 1. Ward, T. et al. (1994) The EMBO journal 13, 5070-4. PMID: 7525274 2. Ozen, A. et al. (2017) The New England journal of medicine 377, 52-61. PMID: 28657829
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.