Anti-Human CD55/DAF Reference Antibody (PAT SC1, RUO) (HY307026)

Name: Anti-Human CD55/DAF Reference Antibody (PAT SC1, RUO)
Brand: abinScience
SKU: HY307026
Price: 370 USD
Availability: InStock

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Overview

Catalog No.	HY307026
Description	Anti-Human CD55 (PAT SC1) (HY307026) is a research-grade recombinant antibody targeting CD55. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG
Clone ID	PAT SC1
Expression system	Mammalian cells
Clonality	Monoclonal
Target	Complement decay-accelerating factor, CR, DAF, CD55
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P08174
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	PAT-SC1, PATSC1, PATSC1
Background	Complement decay-accelerating factor (CD55) is a ~41 kDa protein. This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage. 1. Ward, T. et al. (1994) The EMBO journal 13, 5070-4. PMID: 7525274 2. Ozen, A. et al. (2017) The New England journal of medicine 377, 52-61. PMID: 28657829
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human CD55 (PAT SC1)

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Datasheet

Anti-Human CD55/DAF Reference Antibody (PAT SC1, RUO).pdf

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Anti-Human CD55/DAF Reference Antibody (PAT SC1, RUO) (HY307026)

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