Anti-Human CD55 Recombinant Antibody (SAA0839), FITC (HY307217)

Name: Anti-Human CD55 Recombinant Antibody (SAA0839), FITC
Brand: abinScience
SKU: HY307217
Price: 223 USD
Availability: InStock

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Overview

Catalog No.	HY307217
Species reactivity	Human
Applications	ELISA, FCM, WB
Host species	Mouse
Isotype	IgG2a
Clone ID	SAA0839
Conjugation	FITC
Clonality	Monoclonal
Target	Complement decay-accelerating factor, CR, DAF, CD55
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), FITC
Accession	P08174
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Complement decay-accelerating factor (CD55) is a ~41 kDa protein. This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage. 1. Ward, T. et al. (1994) The EMBO journal 13, 5070-4. PMID: 7525274 2. Ozen, A. et al. (2017) The New England journal of medicine 377, 52-61. PMID: 28657829
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.