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Anti-Human CEACAM6/CD66c Recombinant Antibody (SAA0029) (HW494107)

Anti-Human CEACAM6/CD66c Recombinant Antibody (SAA0029)
Anti-Human CEACAM6/CD66c Recombinant Antibody (SAA0029)
Anti-Human CEACAM6/CD66c Recombinant Antibody (SAA0029)
Anti-Human CEACAM6/CD66c Recombinant Antibody (SAA0029)
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  • 概要

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  • データシート

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概要
カタログ番号HW494107
種反応性Human
アプリケーションFCM
宿主種Human
クローン性Monoclonal
アイソタイプIgG1, kappa
クローンIDSAA0029
テスト済みアプリケーション FCM
ターゲット Normal cross-reacting antigen, Carcinoembryonic antigen-related cell adhesion molecule 6, CEACAM6, CD66c, NCA, Non-specific crossreacting antigen
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Protein A/G purified from cell culture supernatant.
アクセッション番号 P40199
形態 Liquid
保存バッファー 0.01M PBS pH 7.4

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Cell adhesion molecule CEACAM6 (CD66c) is a ~37 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells.

1. Ordoñez, C. et al. (2000) Cancer research 60, 3419-24. PMID: 10910050
2. Kuroki, M. et al. (2001) Journal of leukocyte biology 70, 543-50. PMID: 11590190
3. Kuijpers, TW. et al. (1992) The Journal of cell biology 118, 457-66. PMID: 1378450
4. Blumenthal, RD. et al. (2005) Cancer research 65, 8809-17. PMID: 16204051
5. Oikawa, S. et al. (1991) The Journal of biological chemistry 266, 7995-8001. PMID: 2022629
6. Oikawa, S. et al. (1989) Biochemical and biophysical research communications 164, 39-45. PMID: 2803308
7. Yamanaka, T. et al. (1996) Protein expression and purification 7, 438-46. PMID: 8776764
注意事項 For research use only.
イメージ
  • Anti-Human CEACAM6/CD66c Recombinant Antibody (SAA0029)

    Bioactivity

    SEC-HPLC detection for Anti-Human CD66c/CEACAM6 Antibody (ABS0697).

  • Anti-Human CEACAM6/CD66c Recombinant Antibody (SAA0029)

    Flow CytoMetry

    Flow-cytometry using anti-human CD66c antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD66c monoclonal antibody (Catalog: HW494107) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

参考文献
Formula
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