



| Numéro de catalogue | HY259023 | ||||||
|---|---|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||||
| Applications | Blocking, ELISA, IHC, WB | ||||||
| Espèce hôte | Mouse | ||||||
| Clonalité | Monoclonal | ||||||
| Isotype | IgG2a, kappa | ||||||
| ID de clone | SAA1375 | ||||||
| Cible | Cold-insoluble globulin, CIG, FN, Fibronectin, FN1, EDB, EDB-FN | ||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||
| Pureté | >95% as determined by SDS-PAGE. | ||||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||||
| Numéro d'accès | P02751 | ||||||
| RRID | Anti-Human EDB/EDB-FN Antibody (SAA1375) (abinScience Cat# HY259023, RRID:AB_3726892) |
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| Forme | Liquid | ||||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| Contexte | Fibronectin (EDB) is a ~272 kDa protein. Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation. _x005F_x005F_x000D_ _x005F_x005F_x000D_1. Owens, RJ. et al. (1986) The EMBO journal 5, 2825-30. PMID: 3024962 _x005F_x005F_x000D_
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2. Garcia-Pardo, A. et al. (1987) The Biochemical journal 241, 923-8. PMID: 3593230 _x005F_x005F_x000D_
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3. Calaycay, J. et al. (1985) The Journal of biological chemistry 260, 12136-41. PMID: 3900070 _x005F_x005F_x000D_
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4. Rostagno, A. et al. (1994) The Journal of biological chemistry 269, 31938-45. PMID: 7989369 _x005F_x005F_x000D_
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5. Su, MT. et al. (2021) International immunology 33, 447-458. PMID: 34089617 | ||||||
| Note | For research use only. |

SDS-PAGE for Anti-Human EDB/EDB-FN Recombinant Antibody (SAA1375)

Detects EDB EDB-FN (Catlog No: HY259022) in indirect ELISA.




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