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| カタログ番号 | HY259023 | ||||||
|---|---|---|---|---|---|---|---|
| 種反応性 | Human | ||||||
| アプリケーション | Blocking, ELISA, IHC, WB | ||||||
| 宿主種 | Mouse | ||||||
| クローン性 | Monoclonal | ||||||
| アイソタイプ | IgG2a, kappa | ||||||
| クローンID | SAA1375 | ||||||
| ターゲット | Cold-insoluble globulin, CIG, FN, Fibronectin, FN1, EDB, EDB-FN | ||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||||
| アクセッション番号 | P02751 | ||||||
| RRID | Anti-Human EDB/EDB-FN Antibody (SAA1375) (abinScience Cat# HY259023, RRID:AB_3726892) |
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| 形態 | Liquid | ||||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 背景 | Fibronectin (EDB) is a ~272 kDa protein. Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation. _x005F_x005F_x000D_ _x005F_x005F_x000D_1. Owens, RJ. et al. (1986) The EMBO journal 5, 2825-30. PMID: 3024962 _x005F_x005F_x000D_
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2. Garcia-Pardo, A. et al. (1987) The Biochemical journal 241, 923-8. PMID: 3593230 _x005F_x005F_x000D_
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3. Calaycay, J. et al. (1985) The Journal of biological chemistry 260, 12136-41. PMID: 3900070 _x005F_x005F_x000D_
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4. Rostagno, A. et al. (1994) The Journal of biological chemistry 269, 31938-45. PMID: 7989369 _x005F_x005F_x000D_
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5. Su, MT. et al. (2021) International immunology 33, 447-458. PMID: 34089617 | ||||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human EDB/EDB-FN Recombinant Antibody (SAA1375)
Detects EDB EDB-FN (Catlog No: HY259022) in indirect ELISA.
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
