Anti-Human EMP2 Polyclonal Antibody (HX012014)

Name: Anti-Human EMP2 Polyclonal Antibody
Brand: abinScience
SKU: HX012014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

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Referencias
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SDS

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Número de catálogo

HX012014

Descripción

Anti-Human EMP2 Polyclonal Antibody (HX012014) is a rabbit polyclonal antibody detecting Epithelial membrane protein 2; EMP-2; Protein XMP; EMP2; XMP in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant human EMP2 (Ile21-Thr67).

Objetivo

Epithelial membrane protein 2; EMP-2; Protein XMP; EMP2; XMP

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

P54851

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Epithelial membrane protein 2 (EMP2) is a ~19 kDa protein. Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the alveolar lumen, potentially via mediation of cell surface expression of adhesion markers and lipid raft formation. Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation. Facilitates surface trafficking and formation of lipid rafts bearing GPI-anchor proteins.

1. Gee, HY. et al. (2014) American journal of human genetics 94, 884-90. PMID: 24814193

2. Wadehra, M. et al. (2005) Developmental biology 287, 336-45. PMID: 16216233

3. Morales, SA. et al. (2013) Investigative ophthalmology & visual science 54, 2367-72. PMID: 23439602

4. Fu, M. et al. (2011) PloS one 6, e19945. PMID: 21637765

5. Morales, SA. et al. (2012) Experimental eye research 102, 10-6. PMID: 22728127

6. Morales, SA. et al. (2009) Investigative ophthalmology & visual science 50, 4949-56. PMID: 19494199

7. Wilson, HL. et al. (2002) The Journal of biological chemistry 277, 34017-23. PMID: 12107182

8. Gordon, LK. et al. (2013) Oncogene 32, 5369-76. PMID: 23334331

9. Wadehra, M. et al. (2006) Developmental biology 292, 430-41. PMID: 16487956

Nota

For research use only

Imágenes

Western blot

Lane 1: Mouse spleen lysate

Referencias

Datasheet

Anti-Human EMP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human EMP2 Polyclonal Antibody (HX012014)

Vista general

Imágenes

Referencias

Datasheet

SDS