Anti-Human EMP2 Reference Antibody (PG-101, RUO) (HX012016)

Name: Anti-Human EMP2 Reference Antibody (PG-101, RUO)
Brand: abinScience
SKU: HX012016
Price: 370 USD
Availability: InStock

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Catalog No.	HX012016
Description	Anti-Human EMP2 (PG-101) (HX012016) is a research-grade recombinant antibody targeting Epithelial membrane protein 2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Clonality	Monoclonal
Isotype	IgG
Clone ID	PG-101
Expression system	Mammalian cells
Target	Epithelial membrane protein 2, EMP2, Protein XMP, XMP, EMP-2
Endotoxin level	< 10 EU/mg
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P54851
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	PG-101, PG101, PG101
Background	Epithelial membrane protein 2 (EMP2) is a ~19 kDa protein. Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the alveolar lumen, potentially via mediation of cell surface expression of adhesion markers and lipid raft formation. Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation. Facilitates surface trafficking and formation of lipid rafts bearing GPI-anchor proteins. 1. Gee, HY. et al. (2014) American journal of human genetics 94, 884-90. PMID: 24814193 2. Wadehra, M. et al. (2005) Developmental biology 287, 336-45. PMID: 16216233 3. Morales, SA. et al. (2013) Investigative ophthalmology & visual science 54, 2367-72. PMID: 23439602 4. Fu, M. et al. (2011) PloS one 6, e19945. PMID: 21637765 5. Morales, SA. et al. (2012) Experimental eye research 102, 10-6. PMID: 22728127 6. Morales, SA. et al. (2009) Investigative ophthalmology & visual science 50, 4949-56. PMID: 19494199 7. Wilson, HL. et al. (2002) The Journal of biological chemistry 277, 34017-23. PMID: 12107182 8. Gordon, LK. et al. (2013) Oncogene 32, 5369-76. PMID: 23334331 9. Wadehra, M. et al. (2006) Developmental biology 292, 430-41. PMID: 16487956
Note	For research use only. Not suitable for clinical or therapeutic use.

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Anti-Human EMP2 Reference Antibody (PG-101, RUO).pdf

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Anti-Human EMP2 Reference Antibody (PG-101, RUO) (HX012016)

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