Anti-Human EMP2 Polyclonal Antibody (HX012014)

Name: Anti-Human EMP2 Polyclonal Antibody
Brand: abinScience
SKU: HX012014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HX012014

Description

Anti-Human EMP2 Polyclonal Antibody (HX012014) is a rabbit polyclonal antibody detecting Epithelial membrane protein 2; EMP-2; Protein XMP; EMP2; XMP in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant human EMP2 (Ile21-Thr67).

Target

Epithelial membrane protein 2; EMP-2; Protein XMP; EMP2; XMP

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P54851

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Epithelial membrane protein 2 (EMP2) is a ~19 kDa protein. Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the alveolar lumen, potentially via mediation of cell surface expression of adhesion markers and lipid raft formation. Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation. Facilitates surface trafficking and formation of lipid rafts bearing GPI-anchor proteins.

1. Gee, HY. et al. (2014) American journal of human genetics 94, 884-90. PMID: 24814193

2. Wadehra, M. et al. (2005) Developmental biology 287, 336-45. PMID: 16216233

3. Morales, SA. et al. (2013) Investigative ophthalmology & visual science 54, 2367-72. PMID: 23439602

4. Fu, M. et al. (2011) PloS one 6, e19945. PMID: 21637765

5. Morales, SA. et al. (2012) Experimental eye research 102, 10-6. PMID: 22728127

6. Morales, SA. et al. (2009) Investigative ophthalmology & visual science 50, 4949-56. PMID: 19494199

7. Wilson, HL. et al. (2002) The Journal of biological chemistry 277, 34017-23. PMID: 12107182

8. Gordon, LK. et al. (2013) Oncogene 32, 5369-76. PMID: 23334331

9. Wadehra, M. et al. (2006) Developmental biology 292, 430-41. PMID: 16487956

Note

For research use only

Images

Western blot

Lane 1: Mouse spleen lysate

References

Datasheet

Anti-Human EMP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human EMP2 Polyclonal Antibody (HX012014)

Overview

Images

References

Datasheet

SDS

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